Association of Hygiene Hypothesis with High prevalence of Allergy and Autoimmune Diseases: FMT industry
Abstract
Prevalence of Allergy and Autoimmune Diseases are high in developed countries, but not in developing countries. Helminth infection were associated with lower level of allergy but the mechanism is not yet clear. In hygiene countries like UK, Japan and Korea, Fecal Microbiota Transplantation (FMT) has gained interest as novel therapy and prevention and reach to medicine industrial manufactures. This study will support it by associate Hygiene Hypothesis (HyHy) and the high prevalence of Allergy and Autoimmune Disease. Systematic review and Bayesian network analysis in EBSCO host search engine were used. Result from dyna Med Evidence Based, Point-of-care Reference e Journals: Dentistry, Medical and Nursing has describe 9 literatures support the association of Hy-hy/parasite infection with Allergy and/ or Autoimmune Diseases: 2 publications of meta-analysis are chosen and supported by 5 cross sectional, longitudinal, cause - effect design, and 2 clinical and animal trial. Conclusions: Low-middle-high income countries has a life style of Hyhy pattern support FMT industrial medicine and travelling to developing countries with broad diversity bacteria and worm in therapeutic and prevention potential, supported by sub-saharan and tropical rainforest developing countries.
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Introduction
A firmed increase of global prevalence in allergic diseases mainly among children in the last few decades. Over the years, where several epidemiological studies have reported an inverse association between parasitic worm infections and allergies. The relationship between helminthes infection and allergies is urgent as research aims move to approach the potential of therapy and prevention in using helminths and their products for allergic disorders.1 Using infectious disease high prevalence countries as a source of prevention and treatment of allergy and autoimmune diseases (AD). Knowledge of much references in the association of Hyhy-Allergy2,3,4 Molecular aspect of epitope mapping of bacteria and worm vs. lifestyle in low-middle - high income population are associated with Most of Autoimmune Diseases are costly but Fecal Microbiota Transplantation (FMT) is an effective potential therapy and vaccine.5 Traveling to developing countries with high biodiversity microbiota are also promising.
Conclusion
Low-middle-high income countries has a life style of Hygiene hypothesis. The low - and middle economic income in development countries have similar pattern with population in developing countries, which support FMT industrial medicine and travelling to developing countries. Broad diversity bacteria and worm in therapeutic and prevention potential, supported by sub-saharan and tropical rainforest developing countries .
